The proposed research is aimed towards development of optical biosensor technology for environmental screening of endocrine disruptors. Endocrine disruptors have become a serious environmental threat being a suspect in various reproductive anomalies in wildlife, mimicking the behavior of estrogen and other hormones. The biosensor technology to be developed combines high sensitivity of the surface plasmon resonance (SPR) method with the specificity of artificial receptors based on molecularly imprinted polymers. In the first phase of the research work a laboratory prototype of a novel type of multichannel SPR sensor in which surface plasmons are excited by an optical wave diffracted on an array of multiple gratings will be developed. Then, a miniature version of multichannel SPR sensor device based on integrated optical waveguides supporting long-range surface plasmons and spectral interrogation method will be produced. Simultaneously, biomimetic molecular recognition layers based on polymers with
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