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High-frequency microdevices for controlling protein nanomotors

High-frequency microdevices for controlling protein nanomotors

Provider: Grantová agentura České republiky (GA ČR)
Principal recipient: Institute of Photonics and Electronics of the Czech Academy of Sciences
Investigator:
From: 1. January 2018
To: 31. December 2022
Project number:

Protein motors are biological nanomachines that can directly convert chemical energy into mechanical work. For their application in nanotechnology it is required that their functioning can be controlled. One of the established control methods is the chemical alteration of their structure, which is however cumbersome and resource demanding. Here, we will explore the possibility of controlling the function of nanomotors by pulsed electric field. Using advanced computational and nanofabrication techniques, we will create unique high frequency micro/nanoelectrode integrated fluidic system to deliver ultrashort electric pulses to nanomotors. We will monitor nanomotor function and force-generation on a single molecule level using a combination of advanced nanophotonic tools: single molecule imaging and optical tweezers. We aim to remote control and synchronize the nanomotor force generation with high precision in time. Our results will thus open a new path for the application of these nature designed machines for the construction of bioinspired electromechanical nanosystems.

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