{"id":37400,"date":"2026-09-23T09:49:45","date_gmt":"2026-09-23T07:49:45","guid":{"rendered":"https:\/\/www.ufe.cz\/biosenzor-z-ufe-mezi-15-vybranymi-vedeckymi-vysledky-akademie-ved-za-rok-2025\/"},"modified":"2026-09-30T10:54:12","modified_gmt":"2026-09-30T08:54:12","slug":"biosensor-from-ufe-is-among-the-15-scientific-achievements-selected-by-the-academy-of-sciences-for-2025","status":"publish","type":"post","link":"https:\/\/www.ufe.cz\/en\/biosensor-from-ufe-is-among-the-15-scientific-achievements-selected-by-the-academy-of-sciences-for-2025\/","title":{"rendered":"Biosensor from \u00daFE is among the 15 scientific achievements selected by the Academy of Sciences for 2025"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"37400\" class=\"elementor elementor-37400 elementor-37389\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-27a7c43 e-flex e-con-boxed e-con e-parent\" data-id=\"27a7c43\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d5bd618 elementor-widget elementor-widget-text-editor\" data-id=\"d5bd618\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Highly Sensitive Detection of microRNA<\/h3><p>A research team consisting of Giusy Finocchiaro, Tom\u00e1\u0161 \u0160pringer, Mark\u00e9ta Bockov\u00e1, and Ji\u0159\u00ed Homola from \u00daFE, in collaboration with Zden\u011bk Krej\u010d\u00edk and Michaela Dost\u00e1lov\u00e1 Merkerov\u00e1 from the Institute of Hematology and Blood Transfusion, has developed a rapid and highly sensitive method for detecting microRNAs. The method combines large functional gold nanoparticles with a surface plasmon resonance biosensor. MicroRNAs are small molecules that play a significant role in regulation of biological processes and can serve as biomarkers for various diseases.<\/p><p>A new biosensor detected hsa-miR-451a, a promising biomarker for myelodysplastic neoplasms &#8211; a group of hematopoietic disorders, even at extremely low concentrations. The results, published in the scientific journal <em>Talanta<\/em>, showed that the developed method allows for the determination of physiological concentrations of hsa-miR-451a in human blood plasma. The researchers also demonstrated reduced levels of this microRNA in the blood plasma of patients with myelodysplastic neoplasms compared to healthy individuals.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c9429e8 e-flex e-con-boxed e-con e-parent\" data-id=\"c9429e8\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ba6d200 dce_masking-none elementor-widget elementor-widget-image\" data-id=\"ba6d200\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"308\" src=\"https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-1024x394.png\" class=\"attachment-large size-large wp-image-37394\" alt=\"\" srcset=\"https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-1024x394.png 1024w, https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-300x115.png 300w, https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-768x295.png 768w, https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-1536x591.png 1536w, https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-2048x788.png 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d491e55 e-flex e-con-boxed e-con e-parent\" data-id=\"d491e55\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1766d40 elementor-widget elementor-widget-text-editor\" data-id=\"1766d40\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Publication:<\/strong>\u00a0<span class=\"publikace-autor\">G. Finocchiaro, T. \u0160pringer, Z. Krej\u010d\u00edk, M. Bockov\u00e1, M. Dost\u00e1lov\u00e1 Merkerov\u00e1, J. Homola, <\/span> <span class=\"publikate-title\">&#8220;Large gold nanoparticle release assay for attomolar detection of miRNA related to myelodysplastic neoplasms&#8221;, <\/span> <span class=\"publikace-casopis\">Talanta<\/span> <span class=\"publikace-vydani\">293, <\/span> <span class=\"publikace-strana\">128037 <\/span><span class=\"publikace-rocnik\">(2025) <\/span><span class=\"publikace-doi\">doi:<a href=\"https:\/\/doi.org\/10.1016\/j.talanta.2025.128037\" target=\"_blank\" rel=\"noopener\">10.1016\/j.talanta.2025.128037<\/a><\/span><\/p><p>For more information on these results and other significant scientific achievements of the Academy of Sciences, see the <a href=\"https:\/\/pdf.avcr.cz\/VZ\/2025-EN\/#p=1\" target=\"_blank\" rel=\"noopener\">2025 Annual Report of the Czech Academy of Sciences<\/a>,\u00a0in the chapter <em>Selected Results<\/em>.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>The Czech Academy of Sciences has included a biosensor developed by scientists from the Institute of Photonics and Electronics of the Czech Academy of Sciences as one of its outstanding scientific results of 2025, featured in its annual report. Out of the results from all 54 research institutes of the Academy of Sciences, only 15 has been selected across three research areas. The result, \u201cSurface Plasmon Resonance Biosensor for Sensitive Detection of microRNA,\u201d thus represents a significant recognition of the research team\u2019s work and of \u00daFE\u2019s research in the field of optical biosensors.<\/p>\n","protected":false},"author":7,"featured_media":37420,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[51],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/posts\/37400"}],"collection":[{"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/comments?post=37400"}],"version-history":[{"count":0,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/posts\/37400\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/media\/37420"}],"wp:attachment":[{"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/media?parent=37400"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/categories?post=37400"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/tags?post=37400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}