{"id":37400,"date":"2026-09-23T09:49:45","date_gmt":"2026-09-23T07:49:45","guid":{"rendered":"https:\/\/www.ufe.cz\/biosenzor-z-ufe-mezi-15-vybranymi-vedeckymi-vysledky-akademie-ved-za-rok-2025\/"},"modified":"2026-09-23T15:10:33","modified_gmt":"2026-09-23T13:10:33","slug":"a-biosensor-from-ufe-is-among-the-15-scientific-achievements-selected-by-the-academy-of-sciences-for-2025","status":"publish","type":"post","link":"https:\/\/www.ufe.cz\/en\/a-biosensor-from-ufe-is-among-the-15-scientific-achievements-selected-by-the-academy-of-sciences-for-2025\/","title":{"rendered":"A biosensor from \u00daFE is among the 15 scientific achievements selected by the Academy of Sciences for 2025"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"37400\" class=\"elementor elementor-37400 elementor-37389\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-27a7c43 e-flex e-con-boxed e-con e-parent\" data-id=\"27a7c43\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d5bd618 elementor-widget elementor-widget-text-editor\" data-id=\"d5bd618\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Highly Sensitive Detection of microRNA<\/h3><p>A research team consisting of Giusy Finocchiaro, Tom\u00e1\u0161 \u0160pringer, Mark\u00e9ta Bockov\u00e1, and Ji\u0159\u00ed Homola from \u00daFE, in collaboration with Zden\u011bk Krej\u010d\u00edk and Michaela Dost\u00e1lov\u00e1 Merkerov\u00e1 from the Institute of Hematology and Blood Transfusion, has developed a rapid and highly sensitive method for detecting microRNAs. The method combines large functional gold nanoparticles with a biosensor based on surface plasmon resonance. MicroRNAs are small molecules that play a significant role in regulating biological processes and can serve as biomarkers for various diseases.<\/p><p>A new biosensor has made it possible to detect hsa-miR-451a, a promising biomarker for myelodysplastic neoplasms\u2014a group of hematopoietic disorders\u2014even at extremely low concentrations. The results, published in the scientific journal <em>Talanta<\/em>, showed that the developed method allows for the determination of physiological concentrations of hsa-miR-451a in human blood plasma. The researchers also demonstrated reduced levels of this microRNA in the blood plasma of patients with myelodysplastic neoplasms compared to healthy individuals.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c9429e8 e-flex e-con-boxed e-con e-parent\" data-id=\"c9429e8\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ba6d200 dce_masking-none elementor-widget elementor-widget-image\" data-id=\"ba6d200\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"308\" src=\"https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-1024x394.png\" class=\"attachment-large size-large wp-image-37394\" alt=\"\" srcset=\"https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-1024x394.png 1024w, https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-300x115.png 300w, https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-768x295.png 768w, https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-1536x591.png 1536w, https:\/\/www.ufe.cz\/wp-content\/uploads\/2026\/09\/graphical-abstract-2048x788.png 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d491e55 e-flex e-con-boxed e-con e-parent\" data-id=\"d491e55\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1766d40 elementor-widget elementor-widget-text-editor\" data-id=\"1766d40\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Publication:<\/strong>\u00a0<span class=\"publikace-autor\">G. Finocchiaro, T. \u0160pringer, Z. Krej\u010d\u00edk, M. Bockov\u00e1, M. Dost\u00e1lov\u00e1 Merkerov\u00e1, J. Homola, <\/span> <span class=\"publikate-title\">&#8220;Large gold nanoparticle release assay for attomolar detection of miRNA related to myelodysplastic neoplasms&#8221;, <\/span> <span class=\"publikace-casopis\">Talanta<\/span> <span class=\"publikace-vydani\">293, <\/span> <span class=\"publikace-strana\">128037 <\/span><span class=\"publikace-rocnik\">(2025) <\/span><span class=\"publikace-doi\">doi:<a href=\"https:\/\/doi.org\/10.1016\/j.talanta.2025.128037\" target=\"_blank\" rel=\"noopener\">10.1016\/j.talanta.2025.128037<\/a><\/span><\/p><p>For more information on these results and other significant scientific achievements of the Academy of Sciences, see the <a href=\"https:\/\/pdf.avcr.cz\/VZ\/2025-EN\/#p=1\" target=\"_blank\" rel=\"noopener\">2025 Annual Report of the Czech Academy of Sciences<\/a>,\u00a0in the chapter <em>Selected Results<\/em>.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>The Czech Academy of Sciences has included a biosensor developed by scientists from the Institute of Photonics and Electronics of the Czech Academy of Sciences among the selected scientific achievements of 2025, which it presents in its annual report. Out of the results from all 54 research units of the Academy of Sciences, only 15 were selected across three scientific fields. The inclusion of the \u00daFE\u2019s result, \u201cSurface-Plasmon Biosensor for Sensitive Detection of microRNA,\u201d thus represents a significant recognition of the research team\u2019s work and of \u00daFE\u2019s research in the field of optical biosensors.<\/p>\n","protected":false},"author":7,"featured_media":37420,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[51],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/posts\/37400"}],"collection":[{"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/comments?post=37400"}],"version-history":[{"count":10,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/posts\/37400\/revisions"}],"predecessor-version":[{"id":37424,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/posts\/37400\/revisions\/37424"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/media\/37420"}],"wp:attachment":[{"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/media?parent=37400"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/categories?post=37400"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ufe.cz\/en\/wp-json\/wp\/v2\/tags?post=37400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}