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Tomáš Špringer

Tomáš Špringer, Ph.D.

Tomáš Špringer
Position: Research scientist
Department: Optical Biosensors
+420 266 773 547
springer@ufe.cz
Location: Main building of UFE, Praha 8 - Kobylisy

Research interests:

  • Development of SPR biosensors for ultra-sensitive detection of biomolecules.
  • Development of functional gold nanoparticles for ultra-sensitive SPR biosensors. 
  • Development of microfluidics for SPR biosensors.

Education:

2020–today  Research scientist

2015–2020  Postdoctoral fellow

2006–2015  PhD study, Charles University, Faculty of Mathematics and Physics (Biophysics) at the Institute of Photonics and Electronics, dpt. of Optical Sensors
Thesis: In situ study of interactions of nucleic acids significant in genetic expression and therapy based on its suppression
Supervisor: Prof. Josef Stepanek, PhD.

2001–2006  Master of Science, Charles University, Faculty of Mathematics and Physics (Biophysics)
Thesis: Surface-enhanced photophysical processes of organic molecules in metal nanoparticles
Supervisor: Doc. RNDr. Marek Procházka, Dr.

Awards:

2021: 3rd best scientific publication at the Institute of Photonics and Electronics in 2021
Publication: T.  Špringer, Z. Krejčík, J. Homola: Detecting attomolar concentrations of microRNA related to myelodysplastic syndromes in blood plasma using a novel sandwich assay with nanoparticle release, Biosensors and Bioelectronics 194, 113613 (2021).

2016: Young Scientist Prize of the CSS IEEE EMB 2016 for the best poster presentation
Poster: Functional gold nanoparticles for highly sensitive optical detection of cancer biomarker. T. Špringer, X.C. Song, M.L. Ermini, J. Lamačová, J. Homola. 3BIO: Biophotonics and Bioelectronics for Biomedicine 2016, IPE CAS, Prague, Czech Republic

2010: 2nd poster award, Europt(r)ode X 2010, Prague
Poster: Real-time monitoring of biomolecular interactions in blood plasma using surface plasmon resonance sensor. T. Špringer, M. Piliarik, J. Homola

Active grant projects:

Investigator:

Co-investigator:

National institute for cancer research

Period: 

1. June 2022 –
31. December 2025

Member:

Closed grant projects

Investigator:

Co-investigator:

Member:

Publications

Books:

Book chapters:

Journal papers:

M. Ermini, X. Chadtová Song, T. Špringer and J. Homola, "Peptide Functionalization of Gold Nanoparticles for the Detection of Carcinoembryonic Antigen in Blood Plasma via SPR-Based Biosensor", Frontiers in Chemistry. 7(Feb), 40 (2019) doi:10.3389/fchem.2019.00040
T. Špringer, X. Chadtová Song, M. Ermini, J. Lamačová and J. Homola, "Functional gold nanoparticles for optical affinity biosensing", Analytical and Bioanalytical Chemistry. 409(16), 4087-4097 (2017) doi:10.1007/s00216-017-0355-1
M. Kalousová, S. Dusilová-Sulková, A.A. Kuběna, O. Zakiyanov, K. Levová, M. Bocková, E. Gedeonová, X. Chadtová Song, M. Ermini, T. Špringer, J. Homola, V. Tesař and T. Zima, "Pregnancy-Associated Plasma Protein A2 in Hemodialysis Patients: Significance for Prognosis", Kidney & Blood Pressure Research. 42(3), 509-518 (2017) doi:10.1159/000479847
H. Vaisocherová-Lísalová, F. Surman, I. Víšová, M. Vala, T. Špringer, M. Ermini, H. Šípová, P. Šedivák, M. Houska, T. Riedel, O. Pop-Georgievski, E. Brynda and J. Homola, "Copolymer Brush-Based Ultralow-Fouling Biorecognition Surface Platform for Food Safety", Analytical Chemistry. 88(21), 10533-10539 (2016) doi:10.1021/acs.analchem.6b02617
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