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Tomáš Špringer

Tomáš Špringer, Ph.D.

Tomáš Špringer
Position: Research scientist
Department: Optical Biosensors
+420 266 773 547
springer@ufe.cz
Location: Main building of UFE, Praha 8 - Kobylisy

Research interests:

  • Development of SPR biosensors for ultra-sensitive detection of biomolecules.
  • Development of functional gold nanoparticles for ultra-sensitive SPR biosensors. 
  • Development of microfluidics for SPR biosensors.

Education:

2020–today  Research scientist

2015–2020  Postdoctoral fellow

2006–2015  PhD study, Charles University, Faculty of Mathematics and Physics (Biophysics) at the Institute of Photonics and Electronics, dpt. of Optical Sensors
Thesis: In situ study of interactions of nucleic acids significant in genetic expression and therapy based on its suppression
Supervisor: Prof. Josef Stepanek, PhD.

2001–2006  Master of Science, Charles University, Faculty of Mathematics and Physics (Biophysics)
Thesis: Surface-enhanced photophysical processes of organic molecules in metal nanoparticles
Supervisor: Doc. RNDr. Marek Procházka, Dr.

Awards:

2021: 3rd best scientific publication at the Institute of Photonics and Electronics in 2021
Publication: T.  Špringer, Z. Krejčík, J. Homola: Detecting attomolar concentrations of microRNA related to myelodysplastic syndromes in blood plasma using a novel sandwich assay with nanoparticle release, Biosensors and Bioelectronics 194, 113613 (2021).

2016: Young Scientist Prize of the CSS IEEE EMB 2016 for the best poster presentation
Poster: Functional gold nanoparticles for highly sensitive optical detection of cancer biomarker. T. Špringer, X.C. Song, M.L. Ermini, J. Lamačová, J. Homola. 3BIO: Biophotonics and Bioelectronics for Biomedicine 2016, IPE CAS, Prague, Czech Republic

2010: 2nd poster award, Europt(r)ode X 2010, Prague
Poster: Real-time monitoring of biomolecular interactions in blood plasma using surface plasmon resonance sensor. T. Špringer, M. Piliarik, J. Homola

Active grant projects:

Investigator:

Co-investigator:

National institute for cancer research

Period: 

1. June 2022 –
31. December 2025

Member:

Closed grant projects

Investigator:

Co-investigator:

Member:

Publications

Books:

Book chapters:

Journal papers:

H. Vaisocherová-Lísalová, I. Víšová, M. Ermini, T. Špringer, X. Chadtová Song, J. Mrázek, J. Lamačová, N. Lynn, P. Šedivák and J. Homola, "Low-fouling surface plasmon resonance biosensor for multi-step detection of foodborne bacterial pathogens in complex food samples", Biosensors and Bioelectronics. 80(Jun), 84-90 (2016) doi:10.1016/j.bios.2016.01.040
H. Vaisocherová, H. Šípová, I. Víšová, M. Bocková, T. Špringer, M. Ermini, X. Chadtová Song, Z. Krejčík, L. Chrastinová, O. Pastva, K. Pimková, M. Merkerová-Dostálová, J. E. Dyr and J. Homola, "Rapid and sensitive detection of multiple microRNAs in cell lysate by low-fouling surface plasmon resonance biosensor", Biosensors and Bioelectronics. 70(5 Aug), 226-231 (2015) doi:10.1016/j.bios.2015.03.038
T. Špringer, M. Ermini, B. Špačková, J. Jabloňků and J. Homola, "Enhancing Sensitivity of Surface Plasmon Resonance Biosensors by Functionalized Gold Nanoparticles: Size Matters", Analytical Chemistry. 86(20), 10350-10356 (2014) doi:10.1021/ac502637u
H. Šípová, T. Špringer, D. Rejman, O. Šimák, M. Petrová, P. Novák,   . Rosenbergová, O. Páv, R. Liboska, I. Barvík, J. Štěpánek, I. Rosenberg and J. Homola, "5´-O-Methylphosphonate nucleic acids—new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes", Nucleic Acids Research. 42(8), 5378-5389 (2014) doi:10.1093/nar/gku125
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